Alangium Lamarckii: A Natural Remedy for Inflammation

Abstract

Alangium lamarckii, a medicinal plant indigenous to Balarampur, Uttar Pradesh, has long been used in traditional medicine for its potent anti-inflammatory properties. This study focuses on the formulation, development, and biological evaluation of an anti-inflammatory herbal dosage form derived from Alangium lamarckii. The extraction of active compounds was performed using standard phytochemical methods, followed by the formulation of various dosage forms, including tablets, capsules, and topical applications. The antiinflammatory efficacy of these formulations was assessed through in vitro and in vivo models. Results demonstrated significant inhibition of inflammatory markers, including COX-2 and TNF-α, comparable to conventional non-steroidal anti-inflammatory drugs (NSAIDs). Additionally, the formulations exhibited minimal cytotoxicity and high biocompatibility, making them a promising alternative to synthetic drugs. The study concludes that Alangium lamarckii holds great potential as a natural anti-inflammatory remedy, offering an effective and safer therapeutic option for managing inflammation.