CRISPR-CAS9 IN Oncology: Applications and Ethical Implications in Cancer Gene Editing

Abstract

CRISPR-Cas9, a revolutionary gene-editing technology, holds immense promise in the field of oncology, offering potential breakthroughs in cancer treatment. By enabling precise modifications of the genome, CRISPR-Cas9 offers new avenues for targeting and correcting genetic mutations that drive cancer progression. This paper explores the applications of CRISPR-Cas9 in cancer research and therapy, including tumor suppression, gene therapy, and immune cell enhancement. Additionally, it delves into the ethical concerns surrounding the technology, such as off-target effects, the possibility of germline editing, and the equitable distribution of gene therapies. As cancer remains one of the leading causes of death worldwide, CRISPR-Cas9 provides hope for more personalized and effective treatment options. However, these advancements are accompanied by significant ethical challenges that must be addressed to ensure safe and fair use of gene-editing technologies in clinical settings.